| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | ASGPR/CD301 |
|---|
| Clone | 125A10.03 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, dog |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100μg/50μg |
|---|
| Concentration | n/a |
|---|
| Applications | IHC, FACS surface, WB, antigen capture endocytosis |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | ASGPR/MGL (asialoglycoprotein / macrophage galactose lectin receptor) / CD301 is a Ca(2+)-dependent type II transmembrane lectin. Immunoprecipitation from DCs using anti-DC-ASGPR mAb yields a major 40-kDa protein. ASGPR mRNA is observed predominantly in immune tissues (DCs and granulocytes), but not in T, B, or NK cells, or monocytes. ASGPR species are restricted to the CD14-derived DCs obtained from CD34(+) progenitors, while absent from the CD1a-derived subset. Accordingly, both monocyte-derived DCs and tonsillar interstitial-type DCs express ASGPR protein, while Langerhans-type cells do not. ASGPR is a feature of immaturity, as expression is lost upon CD40L activation. In agreement with the presence of tyrosine-based and dileucine motifs in the intracytoplasmic domain, mAb against DC-ASGPR is rapidly internalized by DCs at 37 degrees C. Finally, intracellular ASGPR is localized in early endosomes, suggesting that the receptor recycles to the cell surface following internalization of ligand. ASGPR/HML is a feature of immature DCs and a subtype of macrophages, and likely important for the specialized antigen-capture function of DCs.(Valladeau J et al, 2001 J. Immunol.,167: 5767) |
|---|
| Immunogen | n/a |
|---|
| Other Names | ASGPR/MGL (asialoglycoprotein / macrophage galactose lectin receptor) |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | DDX0010 |
|---|
| Price | |
|---|
| Order / More Info | ASGPR/CD301 Antibody from DENDRITICS SAS |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
中文字幕日韩精品人妻在线视频,免费看黄片的网站,亚洲深夜操逼
|
中文在线永久免费观看,口述他用舌头给我添高潮,熟女性爱自拍视频
|
黄色成人网站在线免费观看,在线一区国产,成人短视频在线
|
成人免看一级a一片,男生操女生逼逼,五月丁香婷婷综合激情
|
张津瑜,欧美日韩电影一区,日本AA片
|
黄网在线观看免费,雷神吃旅行者萝卜视频,操操操操逼
|
日韩三级片在线看,色天堂下载,男女无遮挡羞羞视频在线观看
|
三年极品人妻刺激,欧美三级小视频,女人十八岁毛片
|
看一级僺逼片,国产精品高潮露脸二区炮架,911精品在线
|
国产精品久久久久久久又粗又大,天天操天天干天天爱,99久久久久无码国产精品免费
|
|