| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD80 |
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| Clone | mAb104 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100μg/50μg |
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| Concentration | n/a |
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| Applications | FACS, cell culture |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The CD80 antigen (B7, BB1) recognizes a 60 kDa transmembrane glycoprotein, member of the immunoglobulin family. This molecule shares with CD86 the capability to be the ligand for two structurally similar molecules expressed on T lymphocytes, CD28 and CD152 (CTLA-4). CD80 antigen is expressed on in vitro activated B lymphocytes. It is not expressed on the majority of resting B cells from peripheral blood but identifies a subpopulation of B cells that has been previously activated. The antigen is also expressed by HTLV-1 transformed T cells activated monocytes, and constitutively on dendritic cells. CD80 binding provides costimulatory signals for T cell activation. (Valle A. et al, 1990; Immunology, 69:531-535; Freeman GJ. et al, 1992; Blood, 79:489-494). |
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| Immunogen | n/a |
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| Other Names | B7, BB1 |
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| Gene, Accession # | n/a |
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| Catalog # | DDX0160 |
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| Price | |
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| Order / More Info | CD80 Antibody from DENDRITICS SAS |
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| Product Specific References | n/a |
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