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產(chǎn)品名稱

DC-SIGN/CD209 Antibody from DENDRITICS SAS

產(chǎn)品貨號

DDX0208

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100μg/50μg

產(chǎn)品品牌

DENDRITICS SAS

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	DC-SIGN/CD209
Clone	120C8
Host Species	Mouse
Reactive Species	human
Isotype	IgG2b,k
Format	purified
Size	100μg/50μg
Concentration	n/a
Applications	FACS surface, HIV gp120 binding studies
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	DC-SIGN (``DC Specific, ICAM-3 Grabbing, Nonintegrin'') / CD209 is a type II membrane protein with an external mannose-binding C-type lectin domain, DC-SIGN is expressed by immature and mature dendritic cells (DC). In the skin, DC-SIGN+ DC are exclusively located in the dermis. DC-SIGN binds to ICAM-3 on resting T cells, establishing DC-T cell contact and adaptive immunity. DC-SIGN is a high affinity receptor for HIV gp120, allowing HIV capture and transmission to CD4+ T cells. In addition to HIV, DC-SIGN is a receptor for a number of other viral and cellular pathogens including Mycobacterium tuberculosis, and is a major player in microbial evasion of the immune system. (Geijtenbeek, T and al, Cell, 2000, 100: 587-597- van Kooyk Y and al, Nat Rev Immunol, 2003 3: 697-709).
Immunogen	n/a
Other Names	DC Specific, ICAM-3 Grabbing, Nonentegrin
Gene, Accession #	n/a
Catalog #	DDX0208
Price
Order / More Info	DC-SIGN/CD209 Antibody from DENDRITICS SAS
Product Specific References	n/a
產(chǎn)品資料

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