| 產(chǎn)品詳情 |
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| Antigenic Specificity | APEX1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100μg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC, IF ? WB 1:500 - 1:2000; IF 1:50 - 1:100; IP1:50 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-APEX1 polyclonal antibody. Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. |
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| Immunogen | APEX nuclease (multifunctional DNA repair enzyme) 1 |
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| Other Names | APE, APE1, APEX, APX, HAP1, REF1 |
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| Gene, Accession # | Gene ID: 328, UniProt: P27695 |
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| Catalog # | FNab00479 |
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| Price | |
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| Order / More Info | APEX1 Antibody from FINETEST |
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| Product Specific References | n/a |
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