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產(chǎn)品名稱

Basophils, Human Antibody from HYCULT BIOTECH

產(chǎn)品貨號(hào)

HM2279

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

HYCULT BIOTECH

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	Basophils, Human
Clone	2D7
Host Species	Mouse
Reactive Species	human
Isotype	IgG1
Format	unconjugated
Size	100 μg
Concentration	100 μg/ml
Applications	frozen sections, FC, IF, paraffin sections, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	The monoclonal antibody 2D7- is a specific marker for basophils detecting- a basophil-specific protein of 7.2-7.5 kDa localized in secretory granules. Activated basophils- have been shown to have a reduced staining with the 2D7 antibody consistent with localization of the antigen- to secretory granules. Basophils are multifunctional haematopoietic cells that- secrete a wide variety of proinflammatory- agents upon activation such as histamine and cytokines. Moreover, basophils can induce IgE production by B cells. Under normal conditions basophils are primarily produced in the bone marrow, whereas mature basophils reside in the circulation and can enter tissues at sites of inflammation. Both basophils and mast cells have been implicated in the pathogenesis of allergic inflammation due to the abundant expression of high affinity receptors for IgE. The 2D7 antibody can be used- as a sensitive and precise marker for human basophils- and does not react with lymphocytes, monocytes, eosinophils, neutrophils- or mast cells in immunohistochemistry. Moreover, the antibody is suitable for western blot analysis of the 2D7 antigen.
Immunogen	Lysate of purified basophils
Other Names	n/a
Gene, Accession #	n/a
Catalog #	HM2279
Price
Order / More Info	Basophils, Human Antibody from HYCULT BIOTECH
Product Specific References	n/a
產(chǎn)品資料

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