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產(chǎn)品名稱

Caspase-9, Human Antibody from HYCULT BIOTECH

產(chǎn)品貨號

HM2342

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

HYCULT BIOTECH

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	Caspase-9, Human
Clone	42769
Host Species	Mouse
Reactive Species	human, mouse, rat
Isotype	IgG1
Format	unconjugated
Size	100 μg
Concentration	100 μg/ml
Applications	IP, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	The caspase-9 antibody 3-20 recognizes caspase-9, a member of the cysteine-aspartic acid protease (caspase) family. It is widely expressed and is particularly important during development. Human pro-caspase-9 is a 46 kDa, 416 amino acid (aa) protein and contains one CARD region (aa 192) and catalytic residues at His237 and Cys287. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. The caspase 9 protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
Immunogen	Synthetic peptide
Other Names	Cysteineaspartic acid protease 9, Casp9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF3, Mch6, ICE-like apoptotic protease 6, ICELAP6.
Gene, Accession #	CASP9, MCH6
Catalog #	HM2342
Price
Order / More Info	Caspase-9, Human Antibody from HYCULT BIOTECH
Product Specific References	n/a
產(chǎn)品資料

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