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產(chǎn)品名稱

C5a des Arg, Human, Recombinant from HYCULT BIOTECH

產(chǎn)品貨號

HC2102

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

50 μg

產(chǎn)品品牌

HYCULT BIOTECH

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	C5a des Arg, Human, Recombinant
Description	Complement fragment C5a is a 74-residu glycopolypeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. C5a is a potent chemoattractant and anaphylatoxin that acts on all classes of leukocytes and on many other cell types including endothelial, smooth muscle, kidney, liver, and neural cells. In addition to its proinflammatory effects, C5a has been shown to protect cells against toxic insult and to stimulate proliferation in neurons and hepatocytes, suggesting a wider role for C5a in homeostasis. C5a is rapidly desarginated by serum carboxypeptidase N to the less potent derivate C5a desArg, the first stage in deactivation of anaphylatoxin activity. The C5a desArg form has a different spectrum of bioactivity to intact C5a. Recombinant Human C5a desArg is His-tagged and has the following amino acid sequence: MRGSHHHHHHGSDYDIPTTENLYFQGGSTLQKKIEEIAAKYKHSVVKKCCYDGACVNNDETCEQ RAARISLGPRCIKAFTECCVVASQLRANISHKDMQLG ((His-tag is underlined, bold sequence is tev protease)
Size	50 μg
Concentration	Lyophilized product in 0.005% Tween 80, 2mM reduced L-glutathion, 0.2mM oxidized L-glutathion and 0.1M Tris-Cl buffer, pH 8.0, containing at least 50 μg human C5a desArg.
Applications	n/a
Other Names	n/a
Gene, Accession, CAS #	n/a
Catalog #	HC2102
Price
Order / More Info	C5a des Arg, Human, Recombinant from HYCULT BIOTECH
Product Specific References	n/a
產(chǎn)品資料

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