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產(chǎn)品名稱(chēng)

CpG-DNA, Mouse from HYCULT BIOTECH

產(chǎn)品貨號(hào)

HC4033

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

產(chǎn)品規(guī)格

200 nmol

產(chǎn)品品牌

HYCULT BIOTECH

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	CpG-DNA, Mouse
Description	Bacterial DNA is known to induce acute inflammatory responses. Bacterial DNA acts as a pathogen-associated molecular pattern by virtue of a 20-fold greater frequency of unmethylated CG dinucleotides found in microbial DNA versus vertebrate DNA. Cellular activation by deoxy-cytidylate-phosphate-deoxy-guanylate (CpG)-DNA occurs via the Toll/IL-1R signal pathway. TLR9 appears to be a major component of the CpG-DNA receptor, acting by direct binding to CpG-DNA. The synthetic oligodeoxynucleotides (ODN) contain the proper CpG-DNA motif mimicing the immunostimulatory effects of bacterial DNA. The human optimal CpG motif GTCGTT differs from the optimal mouse CpG motif GACGTT. Non CpG-DNA has been shown to compete with CpG-DNA in in vitro stimulation experiments. This mouse CpG is a 20-mer ODN has the following sequence: 5'-tccatgacgttcctgatgct-3'. Regular letters represent phosphorothiorate linkage.
Size	200 nmol
Concentration	Approximately 200 nmol lyophilized, purified 20-mer CpG ODN.
Applications	functional studies
Other Names	n/a
Gene, Accession, CAS #	n/a
Catalog #	HC4033
Price
Order / More Info	CpG-DNA, Mouse from HYCULT BIOTECH
Product Specific References	n/a
產(chǎn)品資料

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