| 產(chǎn)品詳情 |
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| Antigenic Specificity | APC |
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| Clone | Ali 12-28 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | peroxidase (HRP) conjugate |
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| Size | 50ul |
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| Concentration | 1mg/ml |
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| Applications | ELISA, IHC-Fr, IP, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse anti APC [Ali 12-28]: Horseradish peroxidase (HRP). This antibody recognises adenomatous polyposis coli (APC), a 310kDa protein that functions as a tumour suppressor. APC tumour suppressor gene is mutated in the inherited disease familial adenomatous polyposis (FAP) and in over 80% of colorectal cancers. The antibody Ali 12-28 recognises a region corresponding to nucleotides 135 and 422 of the APC (exons 2-3) in the N-terminus. It detects both normal and mutant-truncated forms of the APC and may be used for the detection of APC expression and APC mutations. Species reactivity: Human. Does not cross react with mouse |
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| Immunogen | N-terminal APC-MBP fusion protein |
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| Other Names | adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; Adenomatous polyposis coli protein; APC; BTPS2; Deleted in polyposis 2.5; DP2; DP2.5; DP3; GS; Protein APC |
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| Gene, Accession # | n/a |
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| Catalog # | IQ615HRP |
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| Price | |
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| Order / More Info | APC Antibody from IMMUQUEST LTD. |
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| Product Specific References | Efstathiou JA, et al. Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. Proc Natl Acad Sci.1998.95(6):3122-7. PMID:9501226 http://www.ncbi.nlm.nih.gov/pubmed/9501226 |
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