| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | AANAT |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | rat |
| Isotype | n/a |
| Format | purified |
| Size | 50 μg |
| Concentration | n/a |
| Applications | Immunofluorescence: 5-10 μg/mL, Western Blot: 0.5 μg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | AANAT Polyclonal Antibody. Pineal gland serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AA-NAT) is an ~23 kDa protein which is the rate-limiting enzyme in melatonin synthesis. Melatonin serves as the hormonal signal of the daily light/dark cycle, or body clock. The nocturnal oscillation in enzyme activity ranges by 10- to 100-fold depending on species among vertebrates. Studies have shown that AA-NAT is regulated by cAMP at both the mRNA and protein levels. AA-NAT has putative protein kinase A (PKA) sites at Thr29 and Ser206. Phosphorylation of AA-NAT at these residues might play a role in protein inactivation via proteasome-dependent degradation. |
| Immunogen | n/a |
| Other Names | Serotonin N-Acetyltransferase |
| Gene, Accession # | Entrez: 25120; Uniprot: Q64666 |
| Catalog # | PA1-762 |
| Price | |
| Order / More Info | AANAT Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
| 產(chǎn)品資料 |
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