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產(chǎn)品名稱

A 83-01 from LIFESPAN BIOSCIENCES INC.

產(chǎn)品貨號

LS-H6345

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

LIFESPAN BIOSCIENCES INC.

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	A 83-01
Description	Purity >95%. A 83-01 is an inhibitor of TGF-Beta type I receptor kinase (ALK5), activin type IB receptor (ALK4), and nodal type I receptor (ALK7) (IC50 s = 12, 45, and 7.5 nM, respectively). It blocks the phosphorylation of SMAD2/3 and inhibits TGF-Beta-induced epithelial-to-mesenchymal transition. It has little effect on bone morphogenic type I receptors, p38 mitogen-activated protein kinase, or ERK. A 83-01 has been used to reprogram fibroblasts into alternative lineages, including neural stem cells and cardiomyocytes.
Size	n/a
Concentration	n/a
Applications	n/a
Other Names	3-(6-methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Gene, Accession, CAS #	CAS: 909910-43-6
Catalog #	LS-H6345
Price
Order / More Info	A 83-01 from LIFESPAN BIOSCIENCES INC.
Product Specific References	n/a
產(chǎn)品資料

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