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產(chǎn)品名稱

A-77-01 from LIFESPAN BIOSCIENCES INC.

產(chǎn)品貨號

LS-H6360

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

LIFESPAN BIOSCIENCES INC.

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Product Name	A-77-01
Description	Purity >98%. A-77-01 is a potent inhibitor of the TGF-Beta1 receptor ALK5 (IC50 = 25 nM). It has no effects on BMP-regulated transcriptional activity or MAPK pathways. A-77-01 efficiently prevents the growth inhibitory effects of TGF-Beta on lung epithelial Mv1Lu cells. It completely blocks phosphorylation of SMAD2 by TGF-Beta in human keratinocyte HaCaT cells at 1 μM. A-77-01 prevents morphological and gene expression changes characteristic of epithelial-to-mesenchymal transition in NMuMG cells treated with TGF-Beta.
Size	n/a
Concentration	n/a
Applications	n/a
Other Names	4-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-quinoline
Gene, Accession, CAS #	CAS: 607737-87-1
Catalog #	LS-H6360
Price
Order / More Info	A-77-01 from LIFESPAN BIOSCIENCES INC.
Product Specific References	n/a
產(chǎn)品資料

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