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產(chǎn)品名稱

17-AAG from LIFESPAN BIOSCIENCES INC.

產(chǎn)品貨號

LS-H1652

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

LIFESPAN BIOSCIENCES INC.

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	17-AAG
Description	Purity >98%. Glendanamycin (GA), a benzoquinone ansamycin antibiotic, interferes with the action of Hsp90 leading to degradation of Hsp90 client proteins. GA itself however has undesirable properties such as poor aqueous solubility and liver toxicity; therefore, numerous analogs have been synthesized, such as 17-AAG. 17-AAG is an HSP-90 inhibitor that displays a 100-fold higher affinity for HSP-90 derived from tumor cells compared to HSP-90 from normal cells. 17-AAG inhibits Akt activation and expression in tumors and synergizes with a number of antitumor agents such as taxol, cisplatin and UCN-01 (400 nM 17-AAG, U937 cells).
Size	n/a
Concentration	n/a
Applications	n/a
Other Names	n/a
Gene, Accession, CAS #	CAS: 75747-14-7
Catalog #	LS-H1652
Price
Order / More Info	17-AAG from LIFESPAN BIOSCIENCES INC.
Product Specific References	n/a
產(chǎn)品資料

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