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產(chǎn)品名稱

AAL-993 from LIFESPAN BIOSCIENCES INC.

產(chǎn)品貨號(hào)

LS-H14579

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

LIFESPAN BIOSCIENCES INC.

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Product Name	AAL-993
Description	Purity >98% by NMR, TLC. AAL-993 inhibits VEGFR-1 (IC50 = 130 nM), VEGFR-2 (IC50 = 23 nM), and VEGFR-3 (IC50 = 18 nM). PDGFR-b, cKit, and CSF-1R are also inhibited at higher concentrations (IC50's 640 nM, 236 nM and 380 nM respectively). Screening studies have shown no inhibitory activity against a range of other kinases. X-Ray crystallography has shown that AAL-993 binds to the catalytic domain of VEGFR-2 when the protein is in an inactive conformation. Cell permeable, active in vivo and in whole animal studies.
Size	n/a
Concentration	n/a
Applications	n/a
Other Names	2-[(4-Pyridyl)methyl]amino-N-[3-(trifluoromethyl)phenyl]benzamide
Gene, Accession, CAS #	CAS: 269390-77-4
Catalog #	LS-H14579
Price
Order / More Info	AAL-993 from LIFESPAN BIOSCIENCES INC.
Product Specific References	n/a
產(chǎn)品資料

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