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產(chǎn)品名稱

AAL-993 from LIFESPAN BIOSCIENCES INC.

產(chǎn)品貨號

LS-H3287

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

LIFESPAN BIOSCIENCES INC.

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	AAL-993
Description	Purity >98% by TLC. AAL-993 is a potent, selective and cell-permeable inhibitor of VEGFR-1 (IC50 = 130 nM), VEGFR-2 (IC50 = 23 nM) and VEGFR-3 (IC50 = 18nM). At higher concentrations it inhibits PDGFR (640 nM), c-Kit (236 nM) and CSF-1R (380 nM). Inactive at other kinases such as EGFR, FGFR-1, CDK-1, Tie-2, c-Met, IGF-1R, c-Src and c-Abl. X-ray crystal studies on AAL-993 complexed to the catalytic domain of diphosphorylated VEGFR- 2 indicates that it binds to an inactive conformation of the protein. AAL-993 inhibits VEGF-induced angiogenesis (mouse model).
Size	n/a
Concentration	n/a
Applications	n/a
Other Names	2-((4-Pyridyl)methyl)amino-N-(3-(trifluoromethyl)phenyl)benzamide
Gene, Accession, CAS #	CAS: 269390-77-4
Catalog #	LS-H3287
Price
Order / More Info	AAL-993 from LIFESPAN BIOSCIENCES INC.
Product Specific References	n/a
產(chǎn)品資料

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