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產(chǎn)品名稱

A 1210477 from TOCRIS BIOSCIENCE

產(chǎn)品貨號

6409/25

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

25 mg

產(chǎn)品品牌

TOCRIS BIOSCIENCE

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	A 1210477
Description	Selective, high affinity Mcl-1 inhibitor (Ki = 454 pM). Disrupts Mcl-BIM complexes (IC50 in low μM range). Also inhibits Mcl-1NOXA interactions. Exhibits no effect on Bcl-XL-Bim or Bcl-X-BCL-Xs interactions. Induces apoptosis in multiple myeloma and non-small cell lung cancer cell lines and exhibits a synergistic effect with NavitoclaxTM to induce apoptosis in vitro. Cell permeable. Purity 98%. MW (observed): 850.04
Size	25 mg
Concentration	n/a
Applications	n/a
Other Names	7-[5-[[4-[4-[(Dimethylamino)sulfonyl]-1-piperazinyl]phenoxy]methyl]-1,3-dimethyl-1H-pyrazol-4-yl]-1-[2-(4-morpholinyl)ethyl]-3-[3-(1-naphthalenyloxy)propyl]-1H-indole-2-carboxylic acid
Gene, Accession, CAS #	CAS: 1668553-26-1
Catalog #	6409/25
Price
Order / More Info	A 1210477 from TOCRIS BIOSCIENCE
Product Specific References	n/a
產(chǎn)品資料

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