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產(chǎn)品名稱

A 485 from TOCRIS BIOSCIENCE

產(chǎn)品貨號(hào)

6387/25

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

25 mg

產(chǎn)品品牌

TOCRIS BIOSCIENCE

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	A 485
Description	Potent and selective p300/CREB-binding protein (CBP) HAT domain inhibitor (IC50 values are 2.6 and 9.8 nM for the CBP-bromodomain HAT-C/H3 (BHC) and p300-BHC domains, respectively). Displays > 1000-fold selectivity over closely related HATs. Suppresses proliferation in several hematological malignancies and AR+ prostate cancer cell lines in vitro. Inhibits tumor growth in a castration-resistant prostate cancer xenograft model. Orally bioavailable. To request the negative control for A 485, please fill out the A 486 request form on the SGC website.. Purity 98%. MW (observed): 536.48
Size	25 mg
Concentration	n/a
Applications	n/a
Other Names	(1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2',4'-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5'-oxazolidine]-3'-acetamide
Gene, Accession, CAS #	CAS: 1889279-16-6
Catalog #	6387/25
Price
Order / More Info	A 485 from TOCRIS BIOSCIENCE
Product Specific References	n/a
產(chǎn)品資料

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