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產(chǎn)品名稱

A 83-01 from TOCRIS BIOSCIENCE

產(chǎn)品貨號

2939/50

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

50 mg

產(chǎn)品品牌

TOCRIS BIOSCIENCE

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	A 83-01
Description	Potent inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-β-induced epithelial-to-mesenchymal transition. Only weakly inhibits ALK-1, -2, -3, -6 and MAPK activity. More potent than SB 431542 (Cat.No. 1614). Inhibits differentiation of rat induced pluripotent stem cells (riPSCs) and increases clonal expansion efficiency. Helps maintain homogeneity and long-term in vitro self-renewal of human iPSCs. Purity 98%. MW (observed): 421.52
Size	50 mg
Concentration	n/a
Applications	n/a
Other Names	3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Gene, Accession, CAS #	CAS: 909910-43-6
Catalog #	2939/50
Price
Order / More Info	A 83-01 from TOCRIS BIOSCIENCE
Product Specific References	PubMed: 20660726, 21305472, 22927969, 23324343, 23666117, 23728301, 23917481, 23935837, 24204693, 24637302, 25064463, 25437872, 25533785, 25557080, 25610469, 25634246, 25693565, 25740845, 25822089, 25870291, 26332312, 26354680, 26365514, 26455412, 26460009, 26677983, 26797458, 27133794, 27320041, 27819344, 28165492, 28669603, 29168693, 29358044
產(chǎn)品資料

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