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        產(chǎn)品名稱 iLite? IL-12 Assay Ready Cells from EAGLE BIOSCIENCES INC.
        產(chǎn)品貨號(hào) BM4012
        產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià),電話:010-67529703
        產(chǎn)品規(guī)格 250 ul
        產(chǎn)品品牌 EAGLE BIOSCIENCES INC.
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Product NameiLite? IL-12 Assay Ready Cells
        DescriptionInterleukin 12 (IL-12) is a 70 kDa cytokine produced principally by macrophages, neutrophils and dendritic cells in response to stimulation by antigen. IL-12 is a T cell-stimulating factor, playing a critical role in the regulation of T-helper 1 cell responses. IL-12 is composed of two subunits, p35 and p40, covalently linked by a single disulfide bond. The p40 subunit, which binds to the receptor chain IL-12Rβ1, is shared with another heterodimeric cytokine, IL-23. However, the two cytokines expert distinct non-redundant biological functions (1). Therapeutic agents targeting both IL-12 and IL-23 cytokines are currently used to treat psoriasis and psoriatic arthritis, and related agents are in clinical testing for a variety of inflammatory disorders (2). iLite? IL-12 Assay Ready Cells are a genetically engineered reporter gene cell line (DT-40, ATCC#CRL-2111) responsive to Interleukin-12 by specific and proportional expression of Firefly Luciferase. Normalization of cell counts and serum matrix effects is obtained by a second reporter gene, a Renilla Luciferase reporter gene construct, under the control of a constitutive promotor.
        Size250 ul
        Concentrationn/a
        ApplicationsRUO
        Other Namesn/a
        Gene, Accession, CAS #n/a
        Catalog #BM4012
        Price
        Order / More InfoiLite&reg; IL-12 Assay Ready Cells from EAGLE BIOSCIENCES INC.
        Product Specific Referencesn/a
        產(chǎn)品資料
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