| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | BRCA1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 100μg |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, IP ? WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:20 - 1:50 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-BRCA1 polyclonal antibody. This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherit |
| Immunogen | breast cancer 1, early onset |
| Other Names | RNF53 |
| Gene, Accession # | Gene ID: 672, UniProt: P38398 |
| Catalog # | FNab00942 |
| Price | |
| Order / More Info | BRCA1 Antibody from FINETEST |
| Product Specific References | n/a |
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