| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD35 (CR1), Human |
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| Clone | 31R |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | unconjugated |
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| Size | 100 μg |
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| Concentration | 100 μg/ml |
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| Applications | frozen sections, FC, immunoassay, IP, paraffin sections, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD35 (CR1) is a type 1 membrane glycoprotein participating in clearance of immune complexes, regulation of autologous complement activation on cell surfaces, and complement-dependent cellular cytotoxicity mediated by leukocytes. CD35 inhibits complement activation by two distinct mechanisms. CD35 is a cofactor for factor I cleavage of C3b, iC3b and C4b. Furthermore CD35 mediates decay-dissociation of C3 and C5 convertases. CD35 is found on erythrocytes, neutrophils, monocytes and dendritic cells. There are four allotypic variants of CD35 (CR1) with different molecular masses: 190 kDa (CR-1A), 220 kDa (CR1-B), 160 kDa (CR1-C) and 250 kDa (CR1-D). The monoclonal antibody 31R binds a single epitope of CR1. |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | HM2107 |
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| Price | |
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| Order / More Info | CD35 (CR1), Human Antibody from HYCULT BIOTECH |
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| Product Specific References | n/a |
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