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產(chǎn)品名稱

CD46, Human Antibody from HYCULT BIOTECH

產(chǎn)品貨號(hào)

HM2103-IA

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

0.5 mg

產(chǎn)品品牌

HYCULT BIOTECH

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	CD46, Human
Clone	M177
Host Species	Mouse
Reactive Species	human
Isotype	IgG1
Format	unconjugated
Size	0.5 mg
Concentration	n/a
Applications	frozen sections, FC, functional studies, immunoassay, IP, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	The monoclonal antibody M177 recognizes CD46, also designated membrane cofactor protein (MCP). CD46 is a 45-70 kDa protein with genetic and tissue-specific heterogeneity.- It is expressed on every cell and tissue, with the exception of erythrocytes. CD46 serves to inhibit complement activation on host tissue. It performs this function by serving as a cofactor which binds to C3b and C4b. This binding is permitted by factor I, a serine protease of plasma, to degrade C3b and C4b and serves to protect the host cell against autologous attack. It also serves as a receptor for measles virus. Four isoforms of CD46 predominate and arise by alternative splicing of a single CD46 gene. CD46 cDNA encodes a signal sequence followed by four complement control protein domains (also called short consensus repeats (SCR)). The monoclonal antibody M177 reacts with the SCR2 domain.
Immunogen	Purified MCP
Other Names	Membrane cofactor protein, TLX, trophoblast leucocyte common antigen.
Gene, Accession #	CD46
Catalog #	HM2103-IA
Price
Order / More Info	CD46, Human Antibody from HYCULT BIOTECH
Product Specific References	n/a
產(chǎn)品資料

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