| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD46, Mouse |
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| Clone | MM1 |
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| Host Species | Rat |
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| Reactive Species | mouse, rat |
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| Isotype | IgG2a |
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| Format | unconjugated |
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| Size | 100 μg |
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| Concentration | 100 μ/ml |
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| Applications | frozen sections, FC, immunoassay, IF, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46. MCP is a type I membrane glycoprotein that consists of four isoforms i.e. two C-isoforms (51-58 kDa) and two BC isoforms (59-68 kDa) which arise by alternative splicing of a single CD46 gene. Membrane cofactor protein is expressed on every cell and tissue, with the exception of erythrocytes. Membrane cofactor protein serves to down-regulate the activation of complement on host tissue. MCP is a cofactor for factor 1-mediated cleavage of C3b and C4b and this way serves to protect the host cell against autologous attack. MCP is a receptor for several pathogens including measles virus, group A Streptococcus pyogenes and pathogenic Neisseria. |
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| Immunogen | Mouse CD46-human Fc fusion protein |
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| Other Names | MCP, CD46, Trophoblast leukocyte common antigen, TLX, measles virus receptor |
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| Gene, Accession # | n/a |
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| Catalog # | HM1118 |
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| Price | |
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| Order / More Info | CD46, Mouse Antibody from HYCULT BIOTECH |
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| Product Specific References | n/a |
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