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產(chǎn)品名稱

C6, Human Antibody from HYCULT BIOTECH

產(chǎn)品貨號

HM2276

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

HYCULT BIOTECH

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	C6, Human
Clone	6-4
Host Species	Mouse
Reactive Species	human, rabbit
Isotype	IgG1
Format	unconjugated
Size	100 μg
Concentration	100 μg/ml
Applications	FC, functional studies, immunoassay, IF, IP, paraffin sections, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	The monoclonal antibody WU 6-4 recognizes C6, one of the components of the terminal complement complex (TCC), also know as the membrane attack complex (MAC). Proteolytic cleavage of C5 by C5 convertase generates C5b which initiates assembly of the C5b-9 MAC. This complex is assembled from five precursor molecules in the serum, finalized with the polymerization of C9 which accompanies insertion of the complex into the cell membrane causing cellular lysis. Polymorphonuclear leukocytes represent a major source of C6. The monoclonal antibody WU 6-4 recognizes native C6 but not C6 after incorporation into the TCC. Furthermore, WU 6-4 is capable of inhibiting C5b6 and TCC formation in the fluid phase and to a lesser extent, haemolysis. Haemolytic activity could be inhibited only when WU 6-4 was introduced before C5b6 formation.
Immunogen	Human C6
Other Names	n/a
Gene, Accession #	n/a
Catalog #	HM2276
Price
Order / More Info	C6, Human Antibody from HYCULT BIOTECH
Product Specific References	n/a
產(chǎn)品資料

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