<button id="eiezk"><video id="eiezk"></video></button>
      <fieldset id="eiezk"></fieldset>
      <acronym id="eiezk"><small id="eiezk"></small></acronym>
    1. <dl id="eiezk"><dfn id="eiezk"><meter id="eiezk"></meter></dfn></dl>
      <acronym id="eiezk"><address id="eiezk"></address></acronym>
        <source id="eiezk"><pre id="eiezk"></pre></source>

        產(chǎn)品名稱 Chlorotyrosine Antibody from HYCULT BIOTECH
        產(chǎn)品貨號(hào) HP5002
        產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià),電話:010-67529703
        產(chǎn)品規(guī)格 100 μg
        產(chǎn)品品牌 HYCULT BIOTECH
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Antigenic SpecificityChlorotyrosine
        Clonepolyclonal
        Host SpeciesRabbit
        Reactive Speciesn/a
        Isotypen/a
        Formatunconjugated
        Size100 μg
        Concentration100 μg/ml
        Applicationsfrozen sections, immunoassay, paraffin sections
        Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
        DescriptionThe polyclonal antibody recognizes 3-chlorotyrosine specific protein adducts that are formed by hypochlorous acid. Polymorphonuclear leukocytes or neutrophils are one of the primary defense mechanisms against invading microorganisms and also involved in the removal of necrotic cells. However, in certain conditions, recruitment of neutrophils may aggravate existing injury. For example, neutrophils are involved in the pathophysiology of hepatic ischemia-reperfusion injury, endotoxin- and sepsis-induced liver failure, alcoholic hepatitis, and certain drug toxicities. The fact that neutrophils accumulate in the liver does not necessarily mean that they cause injury. ICAM-1 and CD18 integrins are involved in the adherence of neutrophils to target cells, e.g., hepatocytes. This results in a long-lasting adherence-dependent oxidant stress, which is a major factor in neutrophil-mediated liver cell killing. Stimulated neutrophils release oxidants, proteases, and other potentially injurious constituents. They generate superoxide radicals and hydrogen peroxide and release MPO, which catalyzes oxidation of chloride by hydrogen peroxide to give hypochlorous acid. This hypochlorous acid can react with proteins to form 3-chlorotyrosine protein adducts. A limitation for investigating the pathophysiological role of neutrophils in vivo is the lack of a reliable biomarker for neutrophil cytotoxicity. Immunohistochemical staining of liver samples with anti 3-chlorotyrosine antibody correlates well with neutrophil-induced liver injury. The polyclonal antibody can be used to assess chlorotyrosine protein adduct formation and is a useful marker of neutrophil-induced liver cell injury in vivo.
        Immunogenn/a
        Other Namesn/a
        Gene, Accession #n/a
        Catalog #HP5002
        Price
        Order / More InfoChlorotyrosine Antibody from HYCULT BIOTECH
        Product Specific Referencesn/a
        產(chǎn)品資料
        <button id="eiezk"><video id="eiezk"></video></button>
            <fieldset id="eiezk"></fieldset>
            <acronym id="eiezk"><small id="eiezk"></small></acronym>
          1. <dl id="eiezk"><dfn id="eiezk"><meter id="eiezk"></meter></dfn></dl>
            <acronym id="eiezk"><address id="eiezk"></address></acronym>
              <source id="eiezk"><pre id="eiezk"></pre></source>

              最近的2019中文字幕免费一页,亚洲妇女下面毛茸茸,几个装修工人把我压在茶几视频 | 天天爽天天爽,国产在线3,国产精品人人妻人色五月 | 老年人镖客视频播放器评测,欧美三级视频,美女小姐姐的I叫逼逼 | 国产白浆在线观看,吃醋惩罚做到哭gl高h,a黄色视频 | 红桃视频乱码一区二区三区,欧美黄色录像大全,三级片www | 欧美色俺去了,美女色网站,欧美老妇人一区二区免费视频 | 91久久久无码精品不卡A片直播,欧美黄色91,激情丁香婷 | 夜夜夜爽,精跪趴灌满h室友4p,狠狠草视频 | 亚洲无码一级,久久黄片,黄色艹逼视频 | 国产做爰XXX18在线观看网站,日韩美女性生活视频,91在线精品秘 一二三区 |