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產(chǎn)品名稱

TNF-alpha, Human Antibody from HYCULT BIOTECH

產(chǎn)品貨號(hào)

HM2010

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

HYCULT BIOTECH

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Antigenic Specificity	TNF-alpha, Human
Clone	52B83
Host Species	Mouse
Reactive Species	human, guinea pig, mouse, rhesus monkey
Isotype	IgG1
Format	unconjugated
Size	100 μg
Concentration	100 μg/ml
Applications	frozen sections, FC, immunoassay, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	The monoclonal antibody 52B83 reacts with tumor necrosis factor alpha (TNF-alpha). TNF-alpha is a homotrimeric 17 kDa protein, that interacts with either one of the two types of TNF-receptors, termed I and II, leading to receptor cross-linking and signal transduction. The receptors differ strongly in their intra-cellular signaling pathways. TNF-alpha was originally described as a highly cytotoxic cytokine for tumor cells, it causes tumor necrosis in vivo and shows cytolytic activity against tumor cells in vitro. Furthermore,- TNF-alpha is found to be a central mediator in many inflammatory and immunological processes. It can be induced by various products of micro-organisms and by various cytokines leading to expression of a wide variety of- cytokines. The pro-inflammatory properties of- TNF-alpha play a central role in several auto-immune diseases such as rheumatoid arthritis and inhibition by neutralizing molecules have been shown to be beneficial in patients.
Immunogen	n/a
Other Names	Tumor Necrosis Factor-alpha, TNF, TNF-SF2, cachectin
Gene, Accession #	n/a
Catalog #	HM2010
Price
Order / More Info	TNF-alpha, Human Antibody from HYCULT BIOTECH
Product Specific References	n/a
產(chǎn)品資料

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