| 產品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | MAdCAM-1, Human |
|---|
| Clone | 314G8 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | unconjugated |
|---|
| Size | 100 μg |
|---|
| Concentration | 100 μg/ml |
|---|
| Applications | frozen sections, functional studies, immunoassay, paraffin sections, WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | The monocolonal antibody 314G8 reacts with human mucosal addressin cell adhesion molecules-1 (MAdCAM-1), a key player in mediating the infiltration of leukocytes into chronically inflamed tissue. MAdCAM-1 is a cell-surface Ig superfamily member composed of two extracellular Ig domains, followed by a mucin-like domain, a transmembrane domain and a short cytoplasmatic domain. It interacts via its N-terminal Ig domain with the lymphocyte homing receptor alpha4beta7, which plays a critical role in forming the gut-associated lymphoid system. MAdCAM-1 promotes the adhesion of T- and B cells, monocytes/macrophages, and potentially eosinophils, basophils, and differentiated mast cells to the vascular endothelium. Mucosal addressin cell adhesion molecule-1 RNA transcripts are predominantly expressed in the small intestine, mesenteric lymph nodes, colon and spleen; and are very weakly expresssed in human pancreas and brain. The monocolonal antibody 314G8 recognizes a site in the N-terminal Ig domain of MAdCAM-1. The monoclonal antibody 314G8 detects MAdCAM-1 on venules in the spleen and small intestine. MAdCAM-1 is strongly expressed in the synovium of osteoarthritis patients, predominantly on the endothelial lining of blood vessels, but also within the vessel lumen. The monoclonal antibody 314G8 may be useful in diagnosis of inflammation in humans by monitoring the presence and levels of MAdCAM-1. |
|---|
| Immunogen | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | HM2207 |
|---|
| Price | |
|---|
| Order / More Info | MAdCAM-1, Human Antibody from HYCULT BIOTECH |
|---|
| Product Specific References | n/a |
|---|
| 產品資料 |
|
亚洲免费视频在线观看,黄色在线国产,美女黄网站免费
|
国产精品无码激情视频,透明人1未删减版啪啪,一级性爱视频网站
|
一区二区三区在线看,抽插久久,欧美日本视频在线
|
操B大全,男生裸体视频,欧美日逼网
免费黄色视频在线,男生插女生逼逼,国语精品自拍
|
日本中文字幕有码,国产污视频网站,亚洲天堂影音先锋
|
午夜91视频,古装一级淫片高清免费观看,午夜福利99
|
9l蝌蚪PORNY中文,久久极品视频,午夜影院黄片
|
综合偷拍,jizzjizzjizz少妇,猫咪AV大香蕉
|
2024AV在线,黄色动态图片,牛牛无码一区二区三区
|
欧美视频一区,被老男人做很舒服,操美女免费视频
|
|