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        產(chǎn)品名稱 Elastase, Human, ELISA kit from HYCULT BIOTECH
        產(chǎn)品貨號 HK319-02
        產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
        產(chǎn)品規(guī)格 2 x 96 det.
        產(chǎn)品品牌 HYCULT BIOTECH
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Product NameElastase, Human, ELISA kit
        DescriptionNeutrophil elastase, a major serine proteinase in man, is predominantly present in the azurophilic granules of neutrophils. Elastase has a broad range of extracellular matrix substrates including elastin, proteoglycans, collagen and fibronectin. The action of elastase is controlled by serine proteinase inhibitors. Elastase, when released during inflammation, is rapidly bound by its two main inhibitors, alpha1-PI and alpha2-macroglobuline to form elastase-inhibitor complexes. In addition, mucosa secretions may contain the locally secreted elastase inhibitors elafin/SKALP and SLPI. When secreted at sites of inflammation elastase can cause severe tissue damage. An important role has been suggested for elastase in various inflammatory disorders, including pulmonary emphysema, sepsis, arthritis, nephritis and certain skin diseases. Elastase induces the production of IL-8 in human bronchial epithelial, a proces that occurs in part through TLR4. In plasma of healthy individuals approx. 55 ng/ml (29 - 86 ng/ml) elastase is present.
        Size2 x 96 det.
        Concentrationn/a
        ApplicationsImmunoassay
        Other NamesSandwich ELISA kit, EIA, enzyme immunoassay, assay
        Gene, Accession, CAS #n/a
        Catalog #HK319-02
        Price
        Order / More InfoElastase, Human, ELISA kit from HYCULT BIOTECH
        Product Specific Referencesn/a
        產(chǎn)品資料
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