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產(chǎn)品名稱(chēng)

FABP4, Mouse, Recombinant from HYCULT BIOTECH

產(chǎn)品貨號(hào)

HC1104

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

50 μg

產(chǎn)品品牌

HYCULT BIOTECH

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	FABP4, Mouse, Recombinant
Description	Adipocyte Fatty Acid Binding Protein (A-FABP), also known as FABP4, aP2 and ALBP, is a 15 kDa protein and is one of the most abundant proteins in mature adipocytes. Human and mouse A-FABP share 91% amino acid sequence homology. Several adipokines from adipose tissues have been identified. The y mediate the cross talk between adipose tissue and the cardiovascular system. This interaction between adipose tissue, macrophages and several inflammatory cells leads to expression of, besides A-FABP, among others TNF-α, IL-6, MCP-1, leptin, lipocalin-2 and Pai-1. A-FABP is expressed in macrophages and lymphocytes. A-FABP plays a role in the intracellular utilization of fatty acids, transport and metabolism. The putative function of A-FABP is to serve as a lipid-binding chaperone for fatty acids. The protein was identified as a cytoplasmic protein, but is also described to be secreted by adipose tissue in the bloodstream. A-FABP have closely been associated with metabolic syndrome, obesity and atherosclerosis. It is considered as a therapeutic target for these processes in animal models. Several groups have demonstrated an association between serum levels of A-FABP and obesity-related cardiometabolic risk factors, endothelial dysfunction and macrovascular complications of diabetes. The proatherogenic activity of A-FABP is mediated by its direct actions on macrophages, independently of lipid metabolism and insulin sensitivity. In line with clinical findings, data from animal studies also supports a role of A-FABP in cardiovascular disease. HC1104 recombinant protein has been isolated from bacteria using affinity purification.
Size	50 μg
Concentration	Recombinant protein derived from E.coli containing at least 50 μg mouse A-FABP.
Applications	n/a
Other Names	Adipocyte-FABP, ALFBP, A-FABP, FABP4, aP2
Gene, Accession, CAS #	n/a
Catalog #	HC1104
Price
Order / More Info	FABP4, Mouse, Recombinant from HYCULT BIOTECH
Product Specific References	n/a
產(chǎn)品資料

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