| 產(chǎn)品詳情 |
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| Antigenic Specificity | AATF |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 μg/mL, Immunofluorescence: 20 μg/mL, Immunohistochemistry: 10 μg/mL, Western Blot: 0.5-2 μg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AATF Polyclonal Antibody. AATF (apoptosis antagonizing transcription factor) was initially discovered as an interaction partner of ZIP kinase (ZIPK), a member of death-associated protein (DAP) kinase family of pro-apoptotic serine/threonine kinases. AATF is a phosphoprotein containing an acidic region and a putative leucine zipper domain and nuclear localization signal, features which are typical of transcription factors. AATF inhibits the ZIPK-mediated pro-apoptotic pathway and may activate other anti-apoptotic pathways. Recently, it has also been shown to protect neural cells against oxidative damage induced by amyloid b-peptide and to inhibit aberrant production of the beta-peptide by interacting with Par-4 (prostate apoptosis response-4 |
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| Immunogen | n/a |
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| Other Names | HSPC277, CHE-1, CHE1, DED; apoptosis-antagonizing transcription factor; protein AATF; rb-binding protein Che-1 |
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| Gene, Accession # | Entrez: 26574, 56321; Uniprot: Q9JKX4, Q9NY61 |
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| Catalog # | PA5-20006 |
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| Price | |
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| Order / More Info | AATF Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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