| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | AATF/Che-1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 100 μL |
| Concentration | n/a |
| Applications | Immunoprecipitation: 2-5 μg/mg lysate, Western Blot: 1:2,000-1:10,000 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | AATF/Che-1 Polyclonal Antibody. AATF (apoptosis antagonizing transcription factor) was initially discovered as an interaction partner of ZIP kinase (ZIPK), a member of death-associated protein (DAP) kinase family of pro-apoptotic serine/threonine kinases. AATF is a phosphoprotein containing an acidic region and a putative leucine zipper domain and nuclear localization signal, features which are typical of transcription factors. AATF inhibits the ZIPK-mediated pro-apoptotic pathway and may activate other anti-apoptotic pathways. Recently, it has also been shown to protect neural cells against oxidative damage induced by amyloid b-peptide and to inhibit aberrant production of the beta-peptide by interacting with Par-4 (prostate apoptosis resp |
| Immunogen | n/a |
| Other Names | HSPC277, CHE-1, CHE1, DED; apoptosis-antagonizing transcription factor; protein AATF; rb-binding protein Che-1 |
| Gene, Accession # | Entrez: 26574; Uniprot: Q9NY61 |
| Catalog # | A301-031A |
| Price | |
| Order / More Info | AATF/Che-1 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
| 產(chǎn)品資料 |
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