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        產(chǎn)品名稱 AAK1 Antibody from LIFESPAN BIOSCIENCES INC.
        產(chǎn)品貨號 LS-C500939
        產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
        產(chǎn)品規(guī)格 n/a
        產(chǎn)品品牌 LIFESPAN BIOSCIENCES INC.
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Antigenic SpecificityAAK1
        Clonepolyclonal
        Host SpeciesRabbit
        Reactive Specieshuman
        Isotypen/a
        Formatfluorescein (FITC) conjugate
        Sizen/a
        Concentrationn/a
        ApplicationsELISA
        Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
        DescriptionAAK1 Antibody (FITC) LS-C500939. Specificity: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2 display similar levels of kinase activity towards AP2M1. Regulates phosphorylation of other AP-2 subunits as well as AP-2 localization and AP-2-mediated internalization of ligand complexes. Phosphorylates NUMB and regulates its cellular localization, promoting NUMB localization to endosomes. Binds to and stabilizes the activated form of NOTCH1, increases its localization in endosomes and regulates its transcriptional activity.
        ImmunogenRecombinant Human AP2-associated protein kinase 1 protein (274-465AA)
        Other NamesAAK1, Adaptor-associated kinase 1, AP2 associated kinase 1, KIAA1048
        Gene, Accession #AAK1, Gene ID: 22848
        Catalog #LS-C500939
        Price
        Order / More InfoAAK1 Antibody from LIFESPAN BIOSCIENCES INC.
        Product Specific Referencesn/a
        產(chǎn)品資料
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