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| Product Name | PSMB8, 73-276aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 25.4 kDa (229aa). Purity >85% by SDS-PAGE. PSMB8, also known as LMP7, belongs to the peptidase T1B family. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PS |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [proteasome (prosome macropain) subunit beta type 8; proteasome (prosome; macropain) subunit; beta type; 8; D6S216; D6S216E; LMP7; MGC1491; PSMB5i] |
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| Gene, Accession, CAS # | PSMB8, Gene ID: 5696, Accession: NP_683720 |
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| Catalog # | MBS205160 |
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| Price | |
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| Order / More Info | PSMB8, 73-276aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Muchamuel T., et al. (2009) Nat. Med. 15:781-787; Kitamura A., et al. (2011) J. Clin. Invest. 121:4150-4160; |
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