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產(chǎn)品名稱

AC 710 from TOCRIS BIOSCIENCE

產(chǎn)品貨號

5013/50

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

50 mg

產(chǎn)品品牌

TOCRIS BIOSCIENCE

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	AC 710
Description	Potent PDGFR family inhibitor (IC50 values are 1.2, 2, 7.7 and 10.5 nM for KIT, FLT3, PDGFRβ and CSF1R respectively; Kd = 1.3 nM for PDGFRα). Exhibits >30-fold selectivity over a panel of other kinases and exhibits no activity against cytochrome P450. Causes tumor regression of leukemia cell xenografts in mice. Also reduces joint swelling and inflammation in a mouse model of collagen-induced arthritis. Orally active. Purity 99%. MW (observed): 562.7
Size	50 mg
Concentration	n/a
Applications	n/a
Other Names	N-[4-[[[[5-(1,1-Dimethethylethyl)-3-isoxazolyl]amino]carbonyl]amino]phenyl]-5-[(1-ethyl-2,2,6,6-tetramethyl-4-piperidinyl)oxy]-2-pyridinecarboxamide
Gene, Accession, CAS #	CAS: 1351522-04-7
Catalog #	5013/50
Price
Order / More Info	AC 710 from TOCRIS BIOSCIENCE
Product Specific References	PubMed: 29571051
產(chǎn)品資料

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