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產(chǎn)品名稱

ORAI3 Antibody from INVITROGEN ANTIBODIES

產(chǎn)品貨號(hào)

MA5-15778

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 ug

產(chǎn)品品牌

INVITROGEN ANTIBODIES

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	ORAI3
Clone	2H2G9
Host Species	Mouse
Reactive Species	human, rat
Isotype	IgG2a
Format	purified
Size	100 ug
Concentration	n/a
Applications	Immunocytochemistry: 5 μg/mL, Immunofluorescence: 5 μg/mL, Immunohistochemistry: 2.5 μg/mL, Western Blot: 2 μg/mL
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	ORAI3 Monoclonal Antibody (2H2G9). Antigen stimulation of immune cells triggers Ca++ entry t hrough Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Na+ currents through ORAI1, 2 and 3 channels were equally inhibited
Immunogen	n/a
Other Names	TMEM142C; protein orai-3; transmembrane protein 142C
Gene, Accession #	Entrez: 309000, 93129; Uniprot: Q6AXR8, Q9BRQ5
Catalog #	MA5-15778
Price
Order / More Info	ORAI3 Antibody from INVITROGEN ANTIBODIES
Product Specific References	n/a
產(chǎn)品資料

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