| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | ORAI3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | purified |
| Size | 100 ug |
| Concentration | n/a |
| Applications | Immunocytochemistry: 5 μg/mL, Immunofluorescence: 10 μg/mL, Western Blot: 2-4 μg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ORAI3 Polyclonal Antibody. Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Na+ currents through ORAI1, 2 and 3 channels were equally inhibited by extra |
| Immunogen | n/a |
| Other Names | TMEM142C; protein orai-3; transmembrane protein 142C |
| Gene, Accession # | Entrez: 269999, 93129; Uniprot: Q6P8G8, Q9BRQ5 |
| Catalog # | PA5-20375 |
| Price | |
| Order / More Info | ORAI3 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
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