| 產品詳情 |
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| Antigenic Specificity | PSA-NCAM |
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| Clone | 12E3 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgM |
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| Format | purified |
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| Size | 25 μg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 μg/mL, Immunofluorescence: 20 μg/mL, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PSA-NCAM Monoclonal Antibody (12E3), eBioscience?. Polysialic acid is a long homopolymer of sialic acid that is negatively charged and is attached to neural cell adhesion molecule (CD56) and serves as a regulator of NCAM function. PSA attachment to NCAM is associated with inhibited adhesion of neural cells. PSA-NCAM expression is highly regulated and corresponds to specific neural developmental windows in which neural precursors are migrating and during the process of axonal sprouting, guidance, and targeting. PSA-NCAM expression is prevalent during development of the brain, but in the adult becomes restricted to regions undergoing self-renewal or exhibiting plasticity such as the olfactory bulb, suprachiasmatic nucleus, hippocampus, |
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| Immunogen | n/a |
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| Other Names | CD56; NCAM1; Neural cell adhesion molecule 1; NCAM-1; Polysialylated-neural cell adhesion molecule; Polysialylated NCAM; PSA NCAM |
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| Gene, Accession # | Entrez: 17967, 24586, 4684; Uniprot: P13591, P13595, P13596 |
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| Catalog # | 14-9118-80 |
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| Price | |
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| Order / More Info | PSA-NCAM Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 28800076 |
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