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產(chǎn)品名稱

FK-866 HCl from ARBOR ASSAYS, INC.

產(chǎn)品貨號(hào)

P006-25MG

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

25 mg

產(chǎn)品品牌

ARBOR ASSAYS, INC.

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Product Name	FK-866 HCl
Description	FK-866 is a selective inhibitor of the nicotinamide pathway dependent NAD+ synthesis, causing NAD+ depletion. Highly specific, non-competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT/NAPRT) for both the substrate complex and the free enzyme (Ki=0.4 nM and Ki?=0.3 nM, respectively). NAD+ depletion by FK-866 directs delayed cell death by apoptosis in Hep-G2 human liver carcinoma cells (IC50=~1 nM). Causes premature senescence in normal human smooth muscle cells, an effect that may be linked to decreased activity of the NAD+-dependent enzyme SIRT1.
Size	25 mg
Concentration	n/a
Applications	Activator or Inhibitor
Other Names	NAMPT inhibitor
Gene, Accession, CAS #	n/a
Catalog #	P006-25MG
Price
Order / More Info	FK-866 HCl from ARBOR ASSAYS, INC.
Product Specific References	n/a
產(chǎn)品資料

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