| Edit |   |
|---|
| Product Name | PFI-2 |
|---|
| Description | PFI-2 is a novel potent and selective SETD7 histone lysine methyltransferase inhibitor (IC50 ~2 nM). It has > 100-fold selectivity over other methyltransferases and other non-epigenetic targets. PFI-2 has been shown to bind to SETD7 by ITC (Kd = 18 nM), and biotinylated PFI-2 interacts with SETD7 in pull-down studies. MW: 499.52. Purity ≥98% by HPLC |
|---|
| Size | 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | (R)-8-fluoro-N-(1-oxo-1-(pyrrolidin-1-yl)-3-(3-(trifluoromethyl)phenyl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide |
|---|
| Gene, Accession, CAS # | CAS: 1627676-59-8 |
|---|
| Catalog # | B1259-25 |
|---|
| Price | |
|---|
| Order / More Info | PFI-2 from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|