| 產(chǎn)品詳情 |
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| Product Name | PFI 1 |
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| Description | Potent BET bromodomain inhibitor; exhibits inhibitory activity at bromodomain-containing protein (BRD) 2 and BRD4 (IC50 values are 98 and 220 nM respectively). Induces apoptosis and G1 cell cycle arrest in BET inhibitor-sensitive cell lines (MV4;11). Also downregulates Aurora B expression in MV4;11 cells. Cell permeable. Purity 98%. MW (observed): 347.39 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide |
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| Gene, Accession, CAS # | CAS: 1403764-72-6 |
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| Catalog # | 4445/10 |
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| Price | |
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| Order / More Info | PFI 1 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23095041, 25713319 |
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