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產(chǎn)品名稱(chēng)

Cytochrome P450 3A4 Inhibitor Screening Kit from CREATIVE BIOMART

產(chǎn)品貨號(hào)

Kit-2142

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

產(chǎn)品規(guī)格

200 assays

產(chǎn)品品牌

CREATIVE BIOMART

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Cytochrome P450 3A4 Inhibitor Screening Kit
Description	CYP3A4 Inhibitor Screening Kit enables rapid screening of drugs and other new chemical entities (NCEs) for compound CYP3A4 interaction in a reliable, high-throughput fluorescence-based assay. The kit provides a yeast microsomal preparation of human CYP3A4 and cytochrome P450 reductase (CPR) enzymes. The assay utilizes a non-fluorescent CYP3A4 substrate that is converted into a highly fluorescent metabolite detected in the visible range (Ex/Em = 535/587 nm), ensuring a high signal-to-background ratio with little interference by autofluorescence. The concentration of fluorogenic substrate used for screening is roughly equivalent to its Km for CYP3A4, facilitating detection of weak competitive inhibitors. The kit contains a complete set of reagents sufficient for performing 200 reactions in a 96-well plate format.
Size	200 assays
Concentration	n/a
Applications	Rapid, high-throughput screening of drugs and novel ligands. Development of structure-activity relationship (SAR) models to predict CYP3A4 inhibition liability of novel compounds.Prediction of adverse drug-drug interaction potential and bioavailability for compounds metabolized by CYP3A4.
Other Names	n/a
Gene, Accession, CAS #	n/a
Catalog #	Kit-2142
Price
Order / More Info	Cytochrome P450 3A4 Inhibitor Screening Kit from CREATIVE BIOMART
Product Specific References	n/a
產(chǎn)品資料

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