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產(chǎn)品名稱(chēng)

ACER1 Antibody from CREATIVE DIAGNOSTICS

產(chǎn)品貨號(hào)

CABT-BL180

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

CREATIVE DIAGNOSTICS

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	ACER1
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human
Isotype	n/a
Format	unconjugated
Size	n/a
Concentration	n/a
Applications	WB, IHC
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Rabbit Anti-Human ACER1 polyclonal antibody for WB, IHC. Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum;corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can;trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and;sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers;regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at;the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is;highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine;(Houben et al., 2006 (PubMed 16477081); Sun et al., 2008 (PubMed 17713573)).
Immunogen	Recombinant Protein
Other Names	n/a
Gene, Accession #	Gene ID: 125981, UniProt: Q8TDN7
Catalog #	CABT-BL180
Price
Order / More Info	ACER1 Antibody from CREATIVE DIAGNOSTICS
Product Specific References	n/a
產(chǎn)品資料

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