日本一级无码,国产一级在线电影,三区视频在线播放,开心激情站,福利一区在线,亚洲不卡视频,中文国产,美女毛片在线

<button id="eiezk"><video id="eiezk"></video></button>

產(chǎn)品名稱

IGFBP-1 ELISA from EAGLE BIOSCIENCES INC.

產(chǎn)品貨號

E01

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

1 x 96 well

產(chǎn)品品牌

EAGLE BIOSCIENCES INC.

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Product Name	IGFBP-1 ELISA
Description	The Eagle Biosciences ELISA for IGFBP-1 is a so-called Sandwich-Assay. It utilizes two specific and high affinity antibodies for this protein. The IGFBP-1 in the sample binds to the immobilized first antibody on the microtiter plate. In the following step, the biotinylated and Streptavidin- Peroxidase conjugated second specific anti-IGFBP-1-Antibody binds in turn to the immobilised IGFBP-1. Finally, the bound peroxidase catalyses the substrate reaction resulting in a colored product. Therefore colour intensity is highly specific and quantitatively depending on the IGFBP-1-level of the samples. Sample Types: serum, plasma, urine, saliva, cell culture. Range: 0.1 - 8ng/mL. Sensitivity: 0.02 ng/mL. Time: 1.75 hours ? The Insulin-like Growth Factors I and - II are free in body fluids and tissues but are bound to specific binding proteins. Until today seven different binding proteins (IGFBP-1 to -7) can be differentiated additionally several IGFBP-related proteins have also been detected. Bioavailability of IGF is regulated by these IGFBPs or better their proteolytic cleavage which reduces affinity to IGF. But the IGFBPs as well as their proteolytic fragments can also exert IGF-independent effects, like influencing cell migration or proliferation. IGFBP-1 (Placental Protein 12) consists of 234 aminoacids and has a molecular weight of approximately 25kDa. The coding DNA region is located on chromosome 7 [1, 2]. IGFBP-1 is mainly synthesized by foetal and adult liver tissue and decidual endometrium. Intensity of Expression varies enduring menstruation with a maximal expression in the late secretory phase [3, 4]. Further IGFBP-1 expression seems to be regulated by Insulin concentration, with Insulin inhibiting the expression. Insulin regulation results in diurnal fluctuations of up to factor 10 [5]. IGFBP-1 is posttranslational modificated by phosphorylation of serine residues 101, 119 and 169. Phosphorylation has physiological relevance as it increases affinity of IGFBP-1 to IGF. In adult humans phosphorylated IGFBP-1 of the liver is the predominant form in circulation. IGFBP-1 produced by endometrial tissue is significantly less phosphorylated than the liver originated form [6].
Size	1 x 96 well
Concentration	n/a
Applications	RUO
Other Names	E01 Insulin like growth factor IGFBP-1, IGF-II, IGF ASSAY EIA ELISA GROWTH IGF IMMUNOASSAY INSULIN INSULIN-LIKE KIT protein
Gene, Accession, CAS #	n/a
Catalog #	E01
Price
Order / More Info	IGFBP-1 ELISA from EAGLE BIOSCIENCES INC.
Product Specific References	n/a
產(chǎn)品資料

<button id="eiezk"><video id="eiezk"></video></button>