| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | RANKL |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 100μg |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, IP ? WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-RANKL polyclonal antibody. This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. T |
| Immunogen | tumor necrosis factor (ligand) superfamily, member 11 |
| Other Names | CD254, hRANKL2, ODF, OPGL, OPTB2, Osteoprotegerin ligand, RANKL, sOdf, TNFSF11, TRANCE |
| Gene, Accession # | Gene ID: 8600, UniProt: O14788 |
| Catalog # | FNab07108 |
| Price | |
| Order / More Info | RANKL Antibody from FINETEST |
| Product Specific References | n/a |
| 產(chǎn)品資料 |
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