| 產(chǎn)品詳情 |
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| Antigenic Specificity | NEDD4L |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100μg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC ? WB 1:500 - 1:2000; IHC 1:50 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-NEDD4L polyclonal antibody. This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
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| Immunogen | neural precursor cell expressed, developmentally down-regulated 4-like |
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| Other Names | KIAA0439, NEDL3 |
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| Gene, Accession # | Gene ID: 23327, UniProt: Q96PU5 |
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| Catalog # | FNab05646 |
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| Price | |
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| Order / More Info | NEDD4L Antibody from FINETEST |
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| Product Specific References | n/a |
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