| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | UPF1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 100μg |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, IF, IP ? WB 1:500 - 1:2000; IHC 1:50 - 1:200 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-UPF1 polyclonal antibody. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. |
| Immunogen | UPF1 regulator of nonsense transcripts homolog (yeast) |
| Other Names | ATP dependent helicase RENT1, FLJ43809, FLJ46894, HUPF1, KIAA0221, NORF1, pNORF1, RENT1, UPF1 |
| Gene, Accession # | Gene ID: 5976, UniProt: Q92900 |
| Catalog # | FNab09270 |
| Price | |
| Order / More Info | UPF1 Antibody from FINETEST |
| Product Specific References | n/a |
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