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| Antigenic Specificity | JAM-A, Mouse |
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| Clone | BV12 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 μg |
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| Concentration | 100 μg/ml |
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| Applications | FC, immunoassay, IF, IP, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Does not react with: human. The monoclonal antibody BV12 recognizes junctional adhesion molecule-A (JAM-A), also known as JAM-1 and the mouse platelet F11-Receptor (F11R), is a cell adhesion molecule (CAM). JAM-A is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular junctions of endothelial cells and epithelial cells. JAM-A belongs together with JAM-B (VE-JAM or JAM-3) and JAM-C (JAM-2) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. In human JAM-A plays a role in platelet aggregation, secretion, adhesion and spreading. |
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| Immunogen | H5V endothelial cells (Ref.1) |
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| Other Names | Junctional adhesion molecule A, Junctional adhesion molecule 1, JAM-1, CD321. |
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| Gene, Accession # | F11r, Jam1, Jcam, Jcam1 |
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| Catalog # | HM1050F |
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| Price | |
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| Order / More Info | JAM-A, Mouse Antibody from HYCULT BIOTECH |
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| Product Specific References | n/a |
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