| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | ABAT |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | purified |
| Size | 100 μL |
| Concentration | n/a |
| Applications | Western Blot: 1:500-1:3000 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ABAT Polyclonal Antibody. 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively sp |
| Immunogen | n/a |
| Other Names | GABA-AT, GABAT, NPD009, (S)-3-amino-2-methylpropionate transaminase, 4-aminobutyrate aminotransferase, mitochondrial, 4-aminobutyrate transaminase, GABA aminotransferase, GABA transaminase, GABA transferase, gamma-amino-N-butyrate transaminase |
| Gene, Accession # | Entrez: 18, 268860, 81632; Uniprot: P50554, P61922, P80404 |
| Catalog # | PA5-27405 |
| Price | |
| Order / More Info | ABAT Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
| 產(chǎn)品資料 |
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