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| Antigenic Specificity | BTF |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:100-1:500, Immunoprecipitation: 1-4 μg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BTF Polyclonal Antibody. BCLAF1 is an intracellular, death promoting transcriptional repressor of survival genes that interacts with several members of the BCL2 family of proteins. It shows homology to the basic leucine zipper (bzip) and MYB DNA binding domains. From recent research it can be concluded that in case of apoptotic cells this protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope. When over expressed this protein induces apoptosis and can be suppressed by co-expression of BCL2 proteins. Also known as BTF, it triggers a proapoptotic signal, potentially helpful to overcome the resistance to STI571. BCLAF1 is found to express mostly in skeletal muscles. |
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| Immunogen | n/a |
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| Other Names | bK211L9.1 |
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| Gene, Accession # | Entrez: 9774; Uniprot: Q9NYF8 |
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| Catalog # | A300-610A |
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| Price | |
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| Order / More Info | BTF Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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