| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD42b |
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| Clone | MM2/174 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 10 μL/1x10^6 cells |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD42b Monoclonal Antibody (MM2/174), APC. CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. CD42b expression and activation seems to be regulated by VEGF and PDGF. CD42b composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions |
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| Immunogen | n/a |
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| Other Names | BSS, CD42B, CD42b-alpha, GP1B, MGC34595, GPIB |
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| Gene, Accession # | Entrez: 2811; Uniprot: P07359 |
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| Catalog # | A15459 |
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| Price | |
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| Order / More Info | CD42b Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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